The real question is Am I able to Write in Multiple Genres?
Ultimately it is your audience that determines the answer to that. However, it is possible that you could end up with a different audience for each genre. In fact, I’d say that is likely that your audiences will change from genre to genre.
Breaking into a new genre (for you) can also be tough. In my case, my primary focus is writing good fiction no matter what the genre. Getting people to like my books is more a matter of marketing than anything else.